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When I first came into this theater– and Dave was still here– we came in on a Saturday morning at 8:00 or something because we had to think about what changes we were going to be making before they left. Colbert said. I walked around stage. I was there with my manager, James Dixon and my wife, Eve. And we just walked around thinking, Where would I want to stand? Stephen Colbert, who hosts “The Late Show,” says the president-elect might want to take a crack at the Constitution before he takes office. The c… find out this hereColbert described searching on the dark stage for the perfect spot until he encountered a large pile of boxes. After removing the boxes, he told Dickerson he found his spot, and he looked down and noticed a red dot that had been hidden by the boxes. I was standing where he [Letterman] stood. interview skills for university studentsThe new Late Show host explained. I thought, Oh, this just feels right, Therere places onstage where you feel like youre communicating with everybody, and its hard to explain. It just feels right. And that spot just felt right.
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A deadly brain tumor Glioblastoma is one of the most common, and most deadly, brain tumors. About 12,000 people in the United States are diagnosed each year. The median survival is about 15 months after diagnosis. Until recently, clinicians and patients pinned their hopes on a class of chemotherapy drugs called anti-angiogenic compounds that are meant to block the growth of new blood vessels into the tumor. Blocking this growth, they believed, should starve the tumors of oxygen and nutrients. However, two large, phase-3 clinical trials recently reported in The New England Journal of Medicine concluded that one such drug, bevacizumab, conferred no survival benefit on glioblastoma patients. Liu, Rubin and their colleagues wondered if there might be a subgroup of glioblastoma patients that could still be helped by the treatment. They studied the medical records and diagnostic images of 69 glioblastoma patients who had been treated at a local medical center and 48 patients from a national database known as The Cancer Genome Atlas. The researchers used specialized software to categorize each patient into one of two groups based on the degree of vascularization of the patients’ brain tumors. Those whose tumors were more highly vascularized — as determined by an imaging technique called perfusion MRI — were significantly more likely to benefit from treatment with anti-angiogenic therapies than those whose tumors were less well vascularized. Differences in glioblastoma biology Perfusion MRIs are routinely conducted as part of the diagnostic procedure for brain tumor patients.
For the original version including any supplementary images or video, visit https://www.eurekalert.org/pub_releases/2016-12/sumc-sgp121516.php